Located approximately 25 minutes on foot from the Padre Pio Wax Museum, the 3-star Hotel Sirios San Giovanni Rotondo offers access to tourist attractions throughout San Giovanni Rotondo. Guests who stay at this San Giovanni Rotondo hotel can park their car on site.

The centre of San Giovanni Rotondo can be reached within a 20-minute walk. The Sanctuary of Saint Matthew on Gargano is 4.2 km from the Sirios San Giovanni Rotondo, which is also situated just a few steps from Sanctuary Of Santa Maria Delle Grazie. There is the Dinosaur Paleontological Museum nearly a 10-minute ride away, and Convento bus station is just 5 minutes on foot from the hotel. The accommodation lies 50 km from Aeroporto di Foggia "Gino Lisa" airport.

Hotel Sirios welcomes guests to 26 rooms fitted with climate control as well as a flat-screen TV with satellite channels. Some rooms include a private bathroom.

An Italian breakfast is served here every morning. Antica Trattoria offers Italian meals and lies in the vicinity of this San Giovanni Rotondo hotel.