Hotel Sollievo San Giovanni Rotondo is 4.2 km from the Sanctuary of Saint Matthew on Gargano, and features currency exchange and a lift onsite. The hotel has an à la carte restaurant serving Italian cuisine and is situated a short way from the Church of Saint Pio of Pietrelcina.

This 3-star hotel is about 50 km from Aeroporto di Foggia "Gino Lisa" airport and within a 10-minute drive of such cultural venues as the Dinosaur Paleontological Museum. Via Crucis Monumentale is within a few blocks of the Sollievo in San Giovanni Rotondo. The property is also within 2 km of Museo delle cere di Padre PIo and Convento bus station is 350 metres away.

The rooms at this hotel include climate control, as well as media facilities like a flat-screen TV with satellite channels. The bathrooms come with a bidet, a walk-in shower, and a separate toilet along with a hair dryer and a shower cap for more comfort.

A stone's throw from Hotel Sollievo, Ristorante I Santi serves Mediterranean dishes.