B&B Porta Grande Mesagne offers easy access to Museo dell'Arte Sacra, which is situated about 5 minutes' walk away. Featuring luggage storage and a barber shop, the bed & breakfast is located just 250 m from Chiesa di Sant'Anna.

Chiesa Della Santissima Annunziata Parish is 10 minutes' stroll away, while Chiesa di San Lorenzo fuori le Mura Museum is in the immediate vicinity of this 3-star hotel. Places of worship to visit 1.1 km from the Porta Grande include the Catholic church "Parrocchia Santuario Mater Domini". For those travelling from afar, Casale airport is 22 minutes' drive away.

This property offers rooms with a patio and a mini-kitchen featuring an air conditioner, along with a flat-screen TV with satellite channels. Guests will make use of a hair dryer and free toiletries in bathrooms equipped with a bidet, a separate toilet, and a shower. Some rooms feature views of the patio.

The street food restaurant Terracotta Food Space lies just a few steps from B&B Porta Grande.