Located 2.3 km from the Urban Forest of Lecce, Serendipity Room Lecce, Vicinissima Al Centro hotel is 5 minutes' walk from the shopping mall "Centrum". Guests who stay at this guest house can park their car nearby.

The Church of S. Antonio a Fulgenzio is about 700 metres away, while Lecce train station is within 2 km of the hotel. The Serendipity Room Lecce, Vicinissima Al Centro also gives access to the Church of Saints Nicolo and Catald, which is a 20-minute walk away. The Must Museum is within a few blocks of this property. Via San Domenico Savio bus stop lies 0.7 km away.

The rooms at Serendipity Room Lecce, Vicinissima Al Centro hotel provide guests with a flat-screen TV with satellite channels, as well as comforts such as climate control. Along with tea and coffee-making facilities, the rooms are furnished with a writing desk. Bathrooms with a separate toilet and a shower, also offer hairdryers and bath sheets.

This hotel is 150 metres from Panificio La Fournaise, that serves Italian cuisine.