Serafino Hotel Lecce provides proximity to the Parco di Belloluogo, which is situated around 25 minutes' walk away. Guests travelling by car can also use a car park nearby.

The centre of Lecce can be reached in 25 minutes' walk of this guest house, and such cultural venues as the archaeological museum "Museo Faggiano" are 2.3 km away. The Porta Rudiae is approximately 5 minutes' drive from the Serafino, while Via Lequile bus stop is nearly 5 minutes away by car. The Historic Center is 2 km from the hotel. This accommodation provides access to Lecce train station, which is 20 minutes' stroll away.

The rooms at Serafino Hotel feature a writing desk, along with sound-proof windows for guests' convenience.

Pizzeria Mediterranea, situated 300 metres away, is a perfect place to enjoy Italian cuisine.