The perfect Regiohotel Manfredi Manfredonia hotel enjoys a strategic location, 3.9 km from places of worship like Basilica of Santa Maria Maggiore di Siponto, and provides guests with a restaurant. Located around a 10-minute drive from Marina del Gargano Port, the 4-star smoke-free hotel faces the garden and features a hammam, a sauna, and a sundeck.

This Manfredonia hotel is ideally situated 4.1 km from Salty Lake Oasis. Statua di Re Manfredi, which is about a 15-minute ride from the Regiohotel Manfredi Manfredonia, is one of nearby attractions. Guests can easily get in touch with the history of Manfredonia by visiting Castle of Manfredonia, located 4.5 km from the accommodation. For those travelling from afar, Aeroporto di Foggia "Gino Lisa" airport is 56 minutes' drive away.

Some of the 256 air-conditioned rooms at Regiohotel Manfredi hotel are furnished with a study desk, and appointed with tea/coffee making equipment. A flat-screen TV with satellite channels, as well as comforts as an air conditioner are also featured. The private bathrooms include a roll-in shower and a sink along with dressing gowns and slippers.

A free continental breakfast is provided daily for all guests. Refreshing snacks and summertime drinks are readily available at the poolside bar onsite. Finger food and ice cream are offered here for all tastes. Manfredi Restaurant with Mediterranean cuisine is located a few steps from the Regiohotel Manfredi.