Palazzo Guido Dependance Hotel Lecce offers quick access to the Sant'Oronzo Square, situated merely 6 minutes' walk away.

The Church of Saints Nicolo and Catald is 900 metres from the bed & breakfast, while the Porta Rudiae is a mere 0.8 km away. You can find the 12-century Castle of Charles V, which is a great place to explore the area, within a few blocks of this Lecce hotel. The Palazzo Guido Dependance Lecce is also about 25 minutes' walk from the Railway Museum of Puglia and City Terminal bus station is 800 metres away. The property is located in Lecce, only 1.6 km from Lecce train station.

This hotel offers rooms with an adjoining terrace and a seating area featuring climate control, along with a flat-screen TV with satellite channels. You will find a refrigerator, an oven, and kitchenware as well. Bathrooms include a bidet and a separate toilet, and such comforts as bathrobes and towels.

Guests may find the cafeteria Caffe Palmieri in close proximity to Palazzo Guido Dependance Hotel.