Masseria Li Reni Manduria hotel is situated in a protected area of Manduria, 3.6 km from the Archaeological Park of Manduria and about 10 minutes' drive from the Manduria Social Winery Cooperative Society. Located within a 6-km distance of the Clock Tower, this Manduria hotel offers views of the garden and a swimming pool.

The hotel is about 55 km from Casale airport and around a 15-minute ride from such cultural venues as the Museum of the Civilization of Primitivo Wine. The Masseria Li Reni is 4 km away from the centre of Manduria.

The property has 12 rooms, some of them comprise a patio and a balcony, and have self-catering options such as a mini-bar and an espresso machine.

A continental breakfast is served every day.