Located just 200 m from the Church of the Most Holy Annunciation, the 3-star Dimora Sant'Anna Mesagne Hotel is a mere 5 minutes' walk from the Messapian Archaeological Site. There is also parking.

This comfortable guest house boasts convenient location a few steps from the Porta Grande. Plus the hotel is only 0.7 km from the Church of San Lorenzo outside the Walls. Along with other cultural attractions the Museum of Sacred Art is nestled right near the Dimora Sant'Anna.

The air-conditioned rooms are fitted with climate control; such modern facilities as a flat-screen TV with satellite channels, and include private bathrooms with a bidet, a separate toilet, and a shower. Along with coffee/tea making facilities, the rooms are furnished with a cupboard. Bathrooms with a bidet, a separate toilet, and a shower, also offer hairdryers and towels. The rooms include views of the city.

An Italian breakfast is offered at the Dimora Sant'Anna Mesagne. Guests can enjoy Italian dishes at Osteria del Vicoletto, which is about 5 minutes' walk away.