Located merely a 9-minute walk from the Baroque church "Basilica of Santa Croce", Casa Di Lillo Hotel Lecce offers access to tourist attractions throughout Lecce. This guest house also includes a car park.

The hotel is about 50 km from Casale airport and in close proximity to such cultural venues as the Sigismondo Castromediano Museum. The Casa Di Lillo is only 1.1 km from the MUSA - Historical-Archaeological Museum of the University of Salento and 0.7 km from the 12-century Castle of Charles V. This accommodation is located a few steps from the Must Museum in Lecce. The nearest bus stop is Porta San Biagio, approximately 300 metres away.

Just around the corner from Casa Di Lillo Hotel, Tormaresca Vino e Cucina serves Mediterranean dishes.