Palazzo Melissano Bed & Breakfast San Cesario di Lecce offers quick access to the Ducal Palace, situated merely 6 minutes' walk away.

The Lecce Cathedral stands about 6 km away, and the Baroque church "Basilica of Santa Croce" is about 7 km from the hotel. Railway Museum of Puglia is also located around 10 minutes by car from this San Cesario di Lecce bed & breakfast. The Palazzo Melissano Bed & Breakfast stands within 8 km of Church of Saint Matthew, popular with pilgrims and tourists alike.

The bakery Natale Pasticceria lies right near the property.