Located 900 metres from the Public Gardens, Ascanio Grandi Hotel Lecce is 6 minutes' walk from the Church of Saint Irene.

This guest house is about 15 km from Galatina airport and just a few steps from such cultural venues as Sigismondo Castromediano Museum. The ancient Roman Theatre is just 250 m from the hotel, and the 12-century Castle of Charles V is 0.7 km away. Parco di Belloluogo can also be found within a few blocks of the Ascanio Grandi. Porta San Biagio bus stop lies 5 minutes' walk away.

Guests can enjoy contemporary cuisine in Tormaresca Vino e Cucina located 50 metres away.