Located 400 m from the Port of Brindisi, the 4-star Apulian House Hotel Brindisi is approximately a 5-minute walk from the 12th-century Brindisi cathedral. The guest house also includes parking.

This Brindisi hotel is about 5 km from Casale airport and in the vicinity of such cultural venues as the Monument to Italian Sailors. The Apulian House Brindisi is a mere 0.8 km from the Church of Saint Benedict and 450 metres from the 16th-century Renaissance-style palace "Palazzo Granafei Nervegna". There is the Castello Svevo di Brindisi a 14-minute stroll away, while Via Porta Lecce bus station is within a few blocks of the accommodation.

The rooms come with tea and coffee making facilities, as well as a flat-screen TV with satellite channels for guests' convenience. An iron and an air conditioner are featured for guests' comfort. A separate toilet and a shower, along with a hair dryer and complimentary toiletries, are also included in the bathrooms.

Piadineria is located next to Apulian House Hotel and serves Italian dishes, within a 400-metre distance of the property.