Located within 200 metres of Via Crucis Monumentale, Affittacamere I Santi San Giovanni Rotondo is a 6-minute walk from Cella di Padre Pio.

Church of Saint Pio of Pietrelcina is 5 minutes' stroll from this hotel, and Santuario San Matteo sul Gargano is 4.2 km away. Gargano is 4.3 km from the guest house. Convento bus station is a short way from the property.

This San Giovanni Rotondo hotel offers rooms with a balcony featuring an air conditioner, along with a flat-screen TV with satellite channels. Bathrooms include a bidet, a separate toilet, and a shower, and such comforts as hair dryers and towels.

The Affittacamere I Santi serves an Italian breakfast every morning. Antica Trattoria offers Italian dishes and lies an 18-minute walk away.